1084Persistence of Meningococcal Antibodies and Response to a Booster Dose after a Two-dose Vaccination Series with Investigational MenABCWY Vaccine Formulations in Adolescents
نویسندگان
چکیده
Dose after a Two-dose Vaccination Series with Investigational MenABCWY Vaccine Formulations in Adolescents Xavier Saez-Llorens, MD; Diana Catalina Aguilera Vaca, MD; Katia Abarca, MD; Emmanuelle Maho, MSc; Linda Han, MD; Igor Smolenov, MD; Peter Dull, MD; Hospital del Niño, Panama City, Panama; Centro de Investigacion, Colombia, Colombia; Pontificia Universidad Catolica de Chile, Santiago, Chile; Novartis Vaccines and Diagnostics Inc., Cambridge, MA
منابع مشابه
Meningococcal conjugate vaccines policy update: booster dose recommendations.
The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention and the American Academy of Pediatrics approved updated recommendations for the use of quadravalent (serogroups A, C, W-135, and Y) meningococcal conjugate vaccines (Menactra [Sanofi Pasteur, Swiftwater, PA] and Menveo [Novartis, Basel, Switzerland]) in adolescents and in people at persistent high...
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Background The duration of infantile hepatitis B vaccination-induced immunity is still unknown. We assessed antibody persistence and immunological memory to hepatitis B 18 years after vaccination during infancy in Iranian young adults at risk of hepatitis B virus infection due to behavioral or occupational exposures. Methods This study was conducted on 395 freshman students of with a history of...
متن کاملSerogroup C meningococcal glycoconjugate vaccine in adolescents: persistence of bactericidal antibodies and kinetics of the immune response to a booster vaccine more than 3 years after immunization.
BACKGROUND The persistence of protection from meningococcal disease following immunization with serogroup C meningococcal (MenC) glycoconjugate vaccines in infancy is short-lived. The duration of protective immunity afforded by these vaccines in other at-risk age groups (i.e., adolescents and young adults) is not known. We evaluated the persistence of bactericidal antibodies following immunizat...
متن کاملPersistence of bactericidal antibodies following early infant vaccination with a serogroup B meningococcal vaccine and immunogenicity of a preschool booster dose.
BACKGROUND The multicomponent serogroup B meningococcal (4CMenB) vaccine was recently licensed for use in Europe. There are currently no data on the persistence of bactericidal antibodies induced by use of this vaccine in infants. Our objective was to evaluate serogroup B-specific bactericidal antibodies in children aged 40-44 months previously vaccinated at 2, 4, 6 and 12 months of age. METH...
متن کاملSafety and immunogenicity of two doses of quadrivalent meningococcal conjugate vaccine or one dose of meningococcal group C conjugate vaccine, both administered concomitantly with routine immunization to 12- to 18-month-old children
OBJECTIVES To describe the immunogenicity and safety of a two-dose series of a quadrivalent meningococcal (serogroups A, C, Y and W) polysaccharide diphtheria toxoid conjugate vaccine (MenACYW-D) administered to toddlers. METHODS Children were randomly assigned (1:1) at study entry to receive MenACYW-D at 12 and 18 months of age (group 1; n=61) or meningococcal serogroup C conjugate vaccine (...
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